WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for the enriched GO category are listed in this table. For each GO category, the first row lists its sub-root (biological process, molecular function, or cellular component), category name, and corresponding GO ID.
The second row lists the following statistics:
Finally, genes in the category are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:biological process       Name:positive regulation of hydrolase activity       ID:GO:0051345
C=440; O=2; E=0.51; R=3.91; rawP=0.0912; adjP=0.2932
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000171056 NA SOX7 SRY (sex determining region Y)-box 7 83595 ENSG00000171056
2  ENSG00000164742 NA ADCY1 adenylate cyclase 1 (brain) 107 ENSG00000164742


Database:biological process       Name:protein metabolic process       ID:GO:0019538
C=3896; O=8; E=4.53; R=1.77; rawP=0.0566; adjP=0.2932
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000077684 NA PHF17 PHD finger protein 17 79960 ENSG00000077684
2  ENSG00000007047 NA MARK4 MAP/microtubule affinity-regulating kinase 4 57787 ENSG00000007047
3  ENSG00000197372 NA ZNF675 zinc finger protein 675 171392 ENSG00000197372
4  ENSG00000159640 NA ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 1636 ENSG00000159640
5  ENSG00000157368 NA IL34 interleukin 34 146433 ENSG00000157368
6  ENSG00000007541 NA PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q 9091 ENSG00000007541
7  ENSG00000003400 NA CASP10 caspase 10, apoptosis-related cysteine peptidase 843 ENSG00000003400
8  ENSG00000164742 NA ADCY1 adenylate cyclase 1 (brain) 107 ENSG00000164742


Database:biological process       Name:negative regulation of nitrogen compound metabolic process       ID:GO:0051172
C=936; O=3; E=1.09; R=2.76; rawP=0.0908; adjP=0.2932
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000141644 NA MBD1 methyl-CpG binding domain protein 1 4152 ENSG00000141644
2  ENSG00000197372 NA ZNF675 zinc finger protein 675 171392 ENSG00000197372
3  ENSG00000171056 NA SOX7 SRY (sex determining region Y)-box 7 83595 ENSG00000171056


Database:biological process       Name:regulation of protein metabolic process       ID:GO:0051246
C=1413; O=4; E=1.64; R=2.44; rawP=0.0745; adjP=0.2932
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000197372 NA ZNF675 zinc finger protein 675 171392 ENSG00000197372
2  ENSG00000159640 NA ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 1636 ENSG00000159640
3  ENSG00000157368 NA IL34 interleukin 34 146433 ENSG00000157368
4  ENSG00000164742 NA ADCY1 adenylate cyclase 1 (brain) 107 ENSG00000164742


Database:biological process       Name:regulation of macromolecule biosynthetic process       ID:GO:0010556
C=3199; O=7; E=3.72; R=1.88; rawP=0.0580; adjP=0.2932
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000137166 NA FOXP4 forkhead box P4 116113 ENSG00000137166
2  ENSG00000077684 NA PHF17 PHD finger protein 17 79960 ENSG00000077684
3  ENSG00000141644 NA MBD1 methyl-CpG binding domain protein 1 4152 ENSG00000141644
4  ENSG00000197372 NA ZNF675 zinc finger protein 675 171392 ENSG00000197372
5  ENSG00000179134 NA SAMD4B sterile alpha motif domain containing 4B 55095 ENSG00000179134
6  ENSG00000167384 NA ZNF180 zinc finger protein 180 7733 ENSG00000167384
7  ENSG00000171056 NA SOX7 SRY (sex determining region Y)-box 7 83595 ENSG00000171056


Database:biological process       Name:positive regulation of programmed cell death       ID:GO:0043068
C=427; O=2; E=0.50; R=4.03; rawP=0.0866; adjP=0.2932
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000007047 NA MARK4 MAP/microtubule affinity-regulating kinase 4 57787 ENSG00000007047
2  ENSG00000003400 NA CASP10 caspase 10, apoptosis-related cysteine peptidase 843 ENSG00000003400


Database:biological process       Name:regulation of cellular process       ID:GO:0050794
C=7687; O=14; E=8.93; R=1.57; rawP=0.0111; adjP=0.2932
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000137166 NA FOXP4 forkhead box P4 116113 ENSG00000137166
2  ENSG00000077684 NA PHF17 PHD finger protein 17 79960 ENSG00000077684
3  ENSG00000007047 NA MARK4 MAP/microtubule affinity-regulating kinase 4 57787 ENSG00000007047
4  ENSG00000141644 NA MBD1 methyl-CpG binding domain protein 1 4152 ENSG00000141644
5  ENSG00000197372 NA ZNF675 zinc finger protein 675 171392 ENSG00000197372
6  ENSG00000179134 NA SAMD4B sterile alpha motif domain containing 4B 55095 ENSG00000179134
7  ENSG00000167384 NA ZNF180 zinc finger protein 180 7733 ENSG00000167384
8  ENSG00000135956 NA TMEM127 transmembrane protein 127 55654 ENSG00000135956
9  ENSG00000171056 NA SOX7 SRY (sex determining region Y)-box 7 83595 ENSG00000171056
10  ENSG00000159640 NA ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 1636 ENSG00000159640
11  ENSG00000164742 NA ADCY1 adenylate cyclase 1 (brain) 107 ENSG00000164742
12  ENSG00000198844 NA ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15 22899 ENSG00000198844
13  ENSG00000157368 NA IL34 interleukin 34 146433 ENSG00000157368
14  ENSG00000003400 NA CASP10 caspase 10, apoptosis-related cysteine peptidase 843 ENSG00000003400


Database:biological process       Name:heterocycle biosynthetic process       ID:GO:0018130
C=3662; O=8; E=4.26; R=1.88; rawP=0.0404; adjP=0.2932
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000137166 NA FOXP4 forkhead box P4 116113 ENSG00000137166
2  ENSG00000077684 NA PHF17 PHD finger protein 17 79960 ENSG00000077684
3  ENSG00000141644 NA MBD1 methyl-CpG binding domain protein 1 4152 ENSG00000141644
4  ENSG00000197372 NA ZNF675 zinc finger protein 675 171392 ENSG00000197372
5  ENSG00000179134 NA SAMD4B sterile alpha motif domain containing 4B 55095 ENSG00000179134
6  ENSG00000167384 NA ZNF180 zinc finger protein 180 7733 ENSG00000167384
7  ENSG00000171056 NA SOX7 SRY (sex determining region Y)-box 7 83595 ENSG00000171056
8  ENSG00000164742 NA ADCY1 adenylate cyclase 1 (brain) 107 ENSG00000164742


Database:biological process       Name:regulation of primary metabolic process       ID:GO:0080090
C=4314; O=10; E=5.01; R=1.99; rawP=0.0111; adjP=0.2932
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000137166 NA FOXP4 forkhead box P4 116113 ENSG00000137166
2  ENSG00000077684 NA PHF17 PHD finger protein 17 79960 ENSG00000077684
3  ENSG00000141644 NA MBD1 methyl-CpG binding domain protein 1 4152 ENSG00000141644
4  ENSG00000197372 NA ZNF675 zinc finger protein 675 171392 ENSG00000197372
5  ENSG00000179134 NA SAMD4B sterile alpha motif domain containing 4B 55095 ENSG00000179134
6  ENSG00000167384 NA ZNF180 zinc finger protein 180 7733 ENSG00000167384
7  ENSG00000171056 NA SOX7 SRY (sex determining region Y)-box 7 83595 ENSG00000171056
8  ENSG00000159640 NA ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 1636 ENSG00000159640
9  ENSG00000157368 NA IL34 interleukin 34 146433 ENSG00000157368
10  ENSG00000164742 NA ADCY1 adenylate cyclase 1 (brain) 107 ENSG00000164742


Database:biological process       Name:cellular biosynthetic process       ID:GO:0044249
C=5068; O=9; E=5.89; R=1.53; rawP=0.0937; adjP=0.2932
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000137166 NA FOXP4 forkhead box P4 116113 ENSG00000137166
2  ENSG00000077684 NA PHF17 PHD finger protein 17 79960 ENSG00000077684
3  ENSG00000141644 NA MBD1 methyl-CpG binding domain protein 1 4152 ENSG00000141644
4  ENSG00000197372 NA ZNF675 zinc finger protein 675 171392 ENSG00000197372
5  ENSG00000179134 NA SAMD4B sterile alpha motif domain containing 4B 55095 ENSG00000179134
6  ENSG00000167384 NA ZNF180 zinc finger protein 180 7733 ENSG00000167384
7  ENSG00000171056 NA SOX7 SRY (sex determining region Y)-box 7 83595 ENSG00000171056
8  ENSG00000007541 NA PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q 9091 ENSG00000007541
9  ENSG00000164742 NA ADCY1 adenylate cyclase 1 (brain) 107 ENSG00000164742


Database:molecular function       Name:peptidase activity, acting on L-amino acid peptides       ID:GO:0070011
C=560; O=2; E=0.66; R=3.03; rawP=0.1395; adjP=0.4657
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000159640 NA ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 1636 ENSG00000159640
2  ENSG00000003400 NA CASP10 caspase 10, apoptosis-related cysteine peptidase 843 ENSG00000003400


Database:molecular function       Name:DNA binding       ID:GO:0003677
C=2309; O=5; E=2.72; R=1.84; rawP=0.1233; adjP=0.4657
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000137166 NA FOXP4 forkhead box P4 116113 ENSG00000137166
2  ENSG00000141644 NA MBD1 methyl-CpG binding domain protein 1 4152 ENSG00000141644
3  ENSG00000197372 NA ZNF675 zinc finger protein 675 171392 ENSG00000197372
4  ENSG00000167384 NA ZNF180 zinc finger protein 180 7733 ENSG00000167384
5  ENSG00000171056 NA SOX7 SRY (sex determining region Y)-box 7 83595 ENSG00000171056


Database:molecular function       Name:receptor binding       ID:GO:0005102
C=1211; O=3; E=1.43; R=2.10; rawP=0.1667; adjP=0.4657
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000159640 NA ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 1636 ENSG00000159640
2  ENSG00000157368 NA IL34 interleukin 34 146433 ENSG00000157368
3  ENSG00000240654 NA C1QTNF9 C1q and tumor necrosis factor related protein 9 338872 ENSG00000240654


Database:molecular function       Name:GTPase regulator activity       ID:GO:0030695
C=446; O=2; E=0.53; R=3.81; rawP=0.0956; adjP=0.4657
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000198844 NA ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15 22899 ENSG00000198844
2  ENSG00000147459 NA DOCK5 dedicator of cytokinesis 5 80005 ENSG00000147459


Database:molecular function       Name:sequence-specific DNA binding transcription factor activity       ID:GO:0003700
C=1009; O=3; E=1.19; R=2.52; rawP=0.1117; adjP=0.4657
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000137166 NA FOXP4 forkhead box P4 116113 ENSG00000137166
2  ENSG00000141644 NA MBD1 methyl-CpG binding domain protein 1 4152 ENSG00000141644
3  ENSG00000171056 NA SOX7 SRY (sex determining region Y)-box 7 83595 ENSG00000171056


Database:molecular function       Name:nucleic acid binding transcription factor activity       ID:GO:0001071
C=1011; O=3; E=1.19; R=2.52; rawP=0.1122; adjP=0.4657
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000137166 NA FOXP4 forkhead box P4 116113 ENSG00000137166
2  ENSG00000141644 NA MBD1 methyl-CpG binding domain protein 1 4152 ENSG00000141644
3  ENSG00000171056 NA SOX7 SRY (sex determining region Y)-box 7 83595 ENSG00000171056


Database:molecular function       Name:metal ion binding       ID:GO:0046872
C=3935; O=7; E=4.63; R=1.51; rawP=0.1566; adjP=0.4657
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000137166 NA FOXP4 forkhead box P4 116113 ENSG00000137166
2  ENSG00000077684 NA PHF17 PHD finger protein 17 79960 ENSG00000077684
3  ENSG00000141644 NA MBD1 methyl-CpG binding domain protein 1 4152 ENSG00000141644
4  ENSG00000197372 NA ZNF675 zinc finger protein 675 171392 ENSG00000197372
5  ENSG00000167384 NA ZNF180 zinc finger protein 180 7733 ENSG00000167384
6  ENSG00000159640 NA ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 1636 ENSG00000159640
7  ENSG00000164742 NA ADCY1 adenylate cyclase 1 (brain) 107 ENSG00000164742


Database:molecular function       Name:cytoskeletal protein binding       ID:GO:0008092
C=638; O=2; E=0.75; R=2.66; rawP=0.1718; adjP=0.4657
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000007047 NA MARK4 MAP/microtubule affinity-regulating kinase 4 57787 ENSG00000007047
2  ENSG00000159640 NA ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 1636 ENSG00000159640


Database:molecular function       Name:zinc ion binding       ID:GO:0008270
C=1999; O=6; E=2.35; R=2.55; rawP=0.0228; adjP=0.4657
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000137166 NA FOXP4 forkhead box P4 116113 ENSG00000137166
2  ENSG00000077684 NA PHF17 PHD finger protein 17 79960 ENSG00000077684
3  ENSG00000141644 NA MBD1 methyl-CpG binding domain protein 1 4152 ENSG00000141644
4  ENSG00000197372 NA ZNF675 zinc finger protein 675 171392 ENSG00000197372
5  ENSG00000167384 NA ZNF180 zinc finger protein 180 7733 ENSG00000167384
6  ENSG00000159640 NA ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 1636 ENSG00000159640


Database:molecular function       Name:peptidase activity       ID:GO:0008233
C=582; O=2; E=0.69; R=2.92; rawP=0.1485; adjP=0.4657
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000159640 NA ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 1636 ENSG00000159640
2  ENSG00000003400 NA CASP10 caspase 10, apoptosis-related cysteine peptidase 843 ENSG00000003400


Database:cellular component       Name:microtubule organizing center       ID:GO:0005815
C=486; O=2; E=0.68; R=2.92; rawP=0.1485; adjP=1.0000
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000129680 NA MAP7D3 MAP7 domain containing 3 79649 ENSG00000129680
2  ENSG00000007047 NA MARK4 MAP/microtubule affinity-regulating kinase 4 57787 ENSG00000007047


Database:cellular component       Name:cytoskeleton       ID:GO:0005856
C=1790; O=2; E=2.52; R=0.79; rawP=1.0000; adjP=1.0000
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000129680 NA MAP7D3 MAP7 domain containing 3 79649 ENSG00000129680
2  ENSG00000007047 NA MARK4 MAP/microtubule affinity-regulating kinase 4 57787 ENSG00000007047


Database:cellular component       Name:nuclear lumen       ID:GO:0031981
C=2737; O=4; E=3.85; R=1.04; rawP=0.5524; adjP=1.0000
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000129680 NA MAP7D3 MAP7 domain containing 3 79649 ENSG00000129680
2  ENSG00000137166 NA FOXP4 forkhead box P4 116113 ENSG00000137166
3  ENSG00000077684 NA PHF17 PHD finger protein 17 79960 ENSG00000077684
4  ENSG00000141644 NA MBD1 methyl-CpG binding domain protein 1 4152 ENSG00000141644


Database:cellular component       Name:nucleoplasm part       ID:GO:0044451
C=820; O=3; E=1.15; R=2.60; rawP=0.1061; adjP=1.0000
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000137166 NA FOXP4 forkhead box P4 116113 ENSG00000137166
2  ENSG00000077684 NA PHF17 PHD finger protein 17 79960 ENSG00000077684
3  ENSG00000141644 NA MBD1 methyl-CpG binding domain protein 1 4152 ENSG00000141644


Database:cellular component       Name:endoplasmic reticulum       ID:GO:0005783
C=1282; O=2; E=1.80; R=1.11; rawP=0.5479; adjP=1.0000
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000007541 NA PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q 9091 ENSG00000007541
2  ENSG00000147378 NA FATE1 fetal and adult testis expressed 1 89885 ENSG00000147378


Database:cellular component       Name:centrosome       ID:GO:0005813
C=376; O=2; E=0.53; R=3.78; rawP=0.0974; adjP=1.0000
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000129680 NA MAP7D3 MAP7 domain containing 3 79649 ENSG00000129680
2  ENSG00000007047 NA MARK4 MAP/microtubule affinity-regulating kinase 4 57787 ENSG00000007047


Database:cellular component       Name:neuron projection       ID:GO:0043005
C=651; O=2; E=0.92; R=2.18; rawP=0.2328; adjP=1.0000
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000007047 NA MARK4 MAP/microtubule affinity-regulating kinase 4 57787 ENSG00000007047
2  ENSG00000198844 NA ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15 22899 ENSG00000198844


Database:cellular component       Name:organelle       ID:GO:0043226
C=10651; O=16; E=14.99; R=1.07; rawP=0.4218; adjP=1.0000
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000137166 NA FOXP4 forkhead box P4 116113 ENSG00000137166
2  ENSG00000077684 NA PHF17 PHD finger protein 17 79960 ENSG00000077684
3  ENSG00000007047 NA MARK4 MAP/microtubule affinity-regulating kinase 4 57787 ENSG00000007047
4  ENSG00000141644 NA MBD1 methyl-CpG binding domain protein 1 4152 ENSG00000141644
5  ENSG00000197372 NA ZNF675 zinc finger protein 675 171392 ENSG00000197372
6  ENSG00000179134 NA SAMD4B sterile alpha motif domain containing 4B 55095 ENSG00000179134
7  ENSG00000167384 NA ZNF180 zinc finger protein 180 7733 ENSG00000167384
8  ENSG00000158683 NA PKD1L1 polycystic kidney disease 1 like 1 168507 ENSG00000158683
9  ENSG00000171056 NA SOX7 SRY (sex determining region Y)-box 7 83595 ENSG00000171056
10  ENSG00000159640 NA ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 1636 ENSG00000159640
11  ENSG00000167210 NA LOXHD1 lipoxygenase homology domains 1 125336 ENSG00000167210
12  ENSG00000007541 NA PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q 9091 ENSG00000007541
13  ENSG00000147378 NA FATE1 fetal and adult testis expressed 1 89885 ENSG00000147378
14  ENSG00000164742 NA ADCY1 adenylate cyclase 1 (brain) 107 ENSG00000164742
15  ENSG00000129680 NA MAP7D3 MAP7 domain containing 3 79649 ENSG00000129680
16  ENSG00000120279 NA MYCT1 myc target 1 80177 ENSG00000120279


Database:cellular component       Name:extracellular region part       ID:GO:0044421
C=1099; O=3; E=1.55; R=1.94; rawP=0.1988; adjP=1.0000
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000159640 NA ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 1636 ENSG00000159640
2  ENSG00000157368 NA IL34 interleukin 34 146433 ENSG00000157368
3  ENSG00000240654 NA C1QTNF9 C1q and tumor necrosis factor related protein 9 338872 ENSG00000240654


Database:cellular component       Name:extracellular region       ID:GO:0005576
C=2140; O=4; E=3.01; R=1.33; rawP=0.3552; adjP=1.0000
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000159640 NA ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 1636 ENSG00000159640
2  ENSG00000157368 NA IL34 interleukin 34 146433 ENSG00000157368
3  ENSG00000101230 NA ISM1 isthmin 1 homolog (zebrafish) 140862 ENSG00000101230
4  ENSG00000240654 NA C1QTNF9 C1q and tumor necrosis factor related protein 9 338872 ENSG00000240654




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).